I guess time will be the only answer to this. I don't think this will be Casio's Waterloo, but who knows?
Yes, it's going to be very interesting to watch things unfold. TI cancelled a very good cas software program for pc's about the time they introduced the nspire. I think it was called "Derive" but I could be wrong about that. The story as I seem to recall is that they wanted to concentrate all their effort on hand helds which I assume are more profitable. Now with the ground swell of enthusiasm for iPads and apps for iPads, it appears that TI bet on the wrong horse but like you said, time will tell.
What I find interesting is that with iPad apps like "Math Studio" and the excellent non-cas calculator apps, all of which are very much less expensive than dedicated hand helds, the only market that TI may wind up with is the engineers that they shunned in favor of concentrating on the high school education market.
Meanwhile, Casio seems to be signaling (with the lack of a color screen on their latest class pad) that they are not going to put any effort into development at this time. That could be because Casios high end calc sales are down as a result of the iPad explosion.
Yep it sure is going to be interesting to see how all this shakes out and I am guessing that TI is in denial right about now. They have always had what I would call a hard nosed and hard headed "my way or the highway additude." It's going to be interesting to see what they do when the highway doesn't go their way. My guess is that like little kids they will collect their toys, quit the game, and go home. That will result in the teachers who foolishly spent their schools money on TI-nspires without any support, but it will also give those teachers a way out. They can blame it all on TI and then get on the iPad band wagon. We shall see.